Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pitx2  paired-like homeodomain transcription factor 2   (Synonyms: Brx1, Brx1a, Brx1b, Munc30, Otlx2, Pitx2a, Pitx2b, Pitx2c, Ptx2, Rieg, solurshin)
Results	Reference
1	J:99227 Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ, PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol. 2005 Jul;19(7):1893-903
1	J:215601 Gage PJ, Kuang C, Zacharias AL, The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea. Dev Dyn. 2014 Nov;243(11):1391-400
1*	J:226376 Hernandez-Torres F, Franco D, Aranega AE, Navarro F, Expression patterns and immunohistochemical localization of PITX2B transcription factor in the developing mouse heart. Int J Dev Biol. 2015;59(4-6):247-54
1	J:240032 Nouri N, Awatramani R, A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons. Development. 2017 Mar 01;144(5):916-927
1	J:326945 Ramirez de Acuna F, Hernandez-Torres F, Rodriguez-Outeirino L, Dominguez JN, Matias-Valiente L, Sanchez-Fernandez C, Franco D, Aranega AE, Pitx2 Differentially Regulates the Distinct Phases of Myogenic Program and Delineates Satellite Cell Lineages During Muscle Development. Front Cell Dev Biol. 2022;10:940622
1	J:342842 Su D, Eliason S, Sun Z, Shao F, Amendt BA, Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023 Nov;299(11):105324
1*	J:141013 Venugopalan SR, Amen MA, Wang J, Wong L, Cavender AC, D'Souza RN, Akerlund M, Brody SL, Hjalt TA, Amendt BA, Novel expression and transcriptional regulation of FoxJ1 during oro-facial morphogenesis. Hum Mol Genet. 2008 Dec 1;17(23):3643-54
1	J:167837 Waite MR, Skidmore JM, Billi AC, Martin JF, Martin DM, GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons. Dev Dyn. 2011 Feb;240(2):333-46
1	J:157468 Zagoraiou L, Akay T, Martin JF, Brownstone RM, Jessell TM, Miles GB, A cluster of cholinergic premotor interneurons modulates mouse locomotor activity. Neuron. 2009 Dec 10;64(5):645-62
1	J:306263 Zhang YH, Xu M, Shi X, Sun XL, Mu W, Wu H, Wang J, Li S, Su P, Gong L, He M, Yao M, Wu QF, Cascade diversification directs generation of neuronal diversity in the hypothalamus. Cell Stem Cell. 2021 Apr 17;